Whole-Room Decontamination for Hospitals & Clinics

Whole-Room Decontamination Systems for Hospitals, Clinics & Cleanrooms

Healthcare and controlled environments demand more than basic surface disinfection. When you are responsible for patient safety, critical procedures, or sterile manufacturing, you need whole-room decontamination systems that deliver validated, repeatable results without damaging sensitive equipment or disrupting operations. ARES Scientific partners with leading manufacturers to provide hydrogen peroxide fogging systems and environmental decontamination solutions that help hospitals, clinics, and cleanroom facilities achieve high-level disinfection with confidence. From patient rooms and operating suites to ISO-classified cleanrooms, our portfolio is designed to support compliance, reduce risk, and streamline workflows.

Whole-Room Decontamination for Hospitals & Clinical Facilities

In hospitals and clinical facilities, the stakes are high. Healthcare-associated infections (HAIs), multi-drug resistant organisms, and high patient throughput put constant pressure on infection prevention teams. Whole-room decontamination systems for hospitals provide a powerful layer of protection that complements manual cleaning and terminal cleaning protocols.

Why Hospitals Need Whole-Room Decontamination

Reduce HAIs and cross-contamination: Achieve consistent, high-level disinfection across all exposed surfaces, including hard-to-reach areas.
Support terminal cleaning: Add a validated, automated step after manual cleaning to standardize outcomes.
Improve room turnover: Use defined decontamination cycles to streamline workflows and reduce downtime between patients.
Enhance staff safety: Limit staff exposure to pathogens by relying on automated, closed-loop decontamination cycles.

Limitations of Manual Spray-and-Wipe Methods

Manual cleaning and disinfection will always play a role in environmental hygiene, but it has inherent limitations. Shadowed areas behind equipment, undersides of surfaces, vents, and high touchpoints can be inconsistently treated. Dwell times may vary from room to room and shift to shift, making it difficult to ensure uniform results. Whole-room fogging or misting systems are designed to close these gaps by delivering a controlled, repeatable process.

Hydrogen Peroxide Fogging Systems for Clinical Settings

Our hydrogen peroxide fogging systems for hospitals and clinics use ultra-fine particles that behave like a gas, allowing the decontaminant to reach exposed surfaces throughout the room. The technology is engineered to be:

Residue-free and non-corrosive when used as directed, supporting use around sensitive medical equipment and electronics.
Highly effective, with documented log reductions against a broad range of pathogens.
Consistent and repeatable, with programmable cycles and integrated monitoring.
Compatible with existing workflows, integrating into established cleaning and infection-prevention protocols.

Ideal Applications in Hospitals & Clinics

Operating rooms (ORs) and procedure suites
Intensive care units (ICUs), NICU and PICU
Isolation rooms and negative-pressure rooms
Emergency department treatment and observation rooms
Oncology, transplant, and high-risk patient care areas
Ambulatory surgery centers and outpatient clinics

Whole-Room Decontamination for Cleanrooms & Controlled Environments

Cleanrooms and controlled environments in pharmaceutical, biotech, and advanced manufacturing facilities must maintain strict contamination control while protecting sensitive equipment, instruments, and materials. Cleanroom decontamination systems based on hydrogen peroxide fogging offer a reliable way to achieve high-level disinfection without compromising the integrity of your controlled space.

Why Cleanrooms Require Advanced Decontamination

Protect critical processes: Reduce microbial contamination risk in aseptic processing, fill-finish, and cell or gene therapy workflows.
Support GMP and regulatory compliance: Incorporate validated decontamination steps into SOPs and audit-ready documentation.
Maintain ISO classifications: Decontaminate rooms and zones without introducing particles or residues that affect classification.
Minimize downtime: Use defined, repeatable cycles to schedule decontamination events with predictable turnaround times.

Hydrogen Peroxide Fogging for Cleanrooms

In cleanrooms and controlled environments, iHP and hydrogen peroxide fogging systems are designed to deliver efficient decontamination while preserving equipment, finishes, and environmental controls. Ultra-fine droplets behave like a gas, helping to:

Reach exposed surfaces in complex layouts, behind equipment, and within challenging airflow patterns.
Provide uniform coverage without pooling or condensation when used within specified parameters.
Leave no visible residue when properly aerated, minimizing impact on materials and surfaces.

Cleanroom & Controlled Environment Applications

ISO 5–8 cleanrooms and support areas
Aseptic processing and sterile manufacturing suites
Fill-finish and packaging lines
Cell and gene therapy, tissue culture, and advanced therapy labs
Quality control, analytical, and microbiology laboratories
Microelectronics, semiconductor, and optics manufacturing environments

Integrating Decontamination Systems into Your Cleanroom Protocols

ARES Scientific works with your team to integrate whole-room decontamination systems into existing SOPs and facility designs. We can assist with equipment selection, room placement considerations, and operational workflows, helping ensure each cycle is safe, effective, and well-documented for internal and external audits.

Why Partner with ARES Scientific for Environment Decontamination Systems?

Application-driven approach: We focus on your environment—hospital, clinic, or cleanroom—and match solutions to your real-world use cases.
Strong manufacturer partnerships: Access vetted, high-performance systems backed by training and support.
Facility-wide perspective: We understand how environment decontamination systems interact with HVAC, room pressurization, and sensitive equipment.
Support from planning through implementation: From early design discussions to post-installation training, ARES is a long-term partner, not just a supplier.

Whether you are upgrading an existing decontamination program or designing a new facility, our team can help you evaluate options and select the right system for your clinical or controlled environment.

Frequently Asked Questions About Whole-Room Decontamination

Do whole-room decontamination systems replace manual cleaning?

No. Whole-room decontamination systems are designed to complement manual cleaning, not replace it. Manual removal of visible soil and organic material is still required. Fogging or mist-based decontamination is typically used as an additional, automated step to standardize and elevate the overall level of disinfection.

Are hydrogen peroxide fogging systems safe for medical and laboratory equipment?

When used according to manufacturer guidelines, hydrogen peroxide fogging systems are engineered to be compatible with a wide range of medical devices, lab instruments, and cleanroom equipment. The use of fine droplets and controlled aeration helps minimize residue and material stress. Your ARES representative can help review compatibility for specific rooms or assets.

How long does a typical decontamination cycle take?

Cycle time depends on room size, layout, ventilation, and target pathogen reduction. Many hospital and cleanroom applications can be completed within a defined window that fits between patient schedules, shifts, or production runs. During system selection, we review your facility requirements to align cycle times with operational needs.

Can these systems be used after construction, renovation, or contamination events?

Yes. Environment decontamination systems are frequently used to decontaminate rooms after construction or renovation, as well as following contamination events or high-risk procedures. Whole-room fogging provides a standardized way to reset the environment before bringing a space back into service.

How do I know which decontamination system is right for my facility?

The right solution depends on your environment type, room sizes, airflow patterns, material sensitivity, and regulatory requirements. ARES Scientific can help evaluate your needs, compare system options, and recommend a configuration that aligns with your infection-prevention or contamination-control strategy.

Will hydrogen peroxide fogging leave residue or cause corrosion?

Modern hydrogen peroxide fogging systems are formulated and validated to minimize residue and corrosion when used as directed. Fine droplets, controlled concentration, and proper aeration help protect metals, finishes, electronics, and optical components. During planning, we review material compatibility and room conditions to ensure the process is appropriate for your space.

Are whole-room decontamination systems accepted by regulators and accreditation bodies?

Whole-room decontamination technologies are widely used in healthcare, pharmaceutical, and biotechnology settings and can support compliance with infection-prevention standards and GMP expectations when integrated into documented SOPs. ARES can help your team incorporate these systems into protocols and validation packages that align with your regulatory and accreditation requirements.

Can the same decontamination technology be used in both small rooms and large facilities?

Many systems can be scaled across different room volumes by adjusting cycle parameters or deploying multiple units. Smaller procedure rooms, isolation rooms, or labs may be treated with a single unit, while larger suites or open areas may require additional capacity or a multi-zone strategy. ARES will work with you to size systems appropriately for your floor plan and throughput. Ready to evaluate whole-room decontamination systems for your hospital, clinic, or cleanroom? Contact ARES Scientific to discuss your applications and connect with a specialist in environmental and whole-room decontamination solutions.

Additional Questions & Answers About Whole-Room Decontamination

What types of pathogens can whole-room decontamination systems eliminate?

Hydrogen peroxide fogging systems are effective against a broad spectrum of pathogens, including bacteria, viruses, fungi, spores, and mycobacteria. Many systems have documented efficacy achieving 6-log reductions against resilient organisms such as C. difficile and Bacillus spores.

Is hydrogen peroxide fogging safe for staff to be around?

Yes. Rooms must be unoccupied during active fogging, but once the aeration cycle is complete and concentrations return to safe levels, the room can be re-entered. Most systems include sensors or cycle validation steps that ensure personnel only return when it is safe to do so.

How long does the room need to remain out of service during a fogging cycle?

Room downtime depends on the room size, air exchanges, chosen concentration, and aeration speed. Many healthcare and cleanroom applications can be treated and returned to service within a predictable window, often between routine schedule gaps or production runs.

Do whole-room decontamination systems require special HVAC modifications?

Most rooms do not require structural changes or HVAC modifications. However, airflow patterns, pressure relationships (positive or negative), and air change rates can influence cycle efficiency. ARES can evaluate your existing HVAC conditions and recommend best practices for effective treatment.

Can hydrogen peroxide fogging be used around electronics and sensitive equipment?

Yes. Modern iHP and non-condensing hydrogen peroxide fogging systems are designed to be compatible with electronics, medical devices, sensors, and laboratory instruments when used correctly. Fine droplets and vapor-like dispersion minimize condensation and pooling.

How often should a facility perform whole-room decontamination?

Frequency depends on risk level, regulatory requirements, occupancy type, and internal protocols. Hospitals may use it after isolation patients, outbreaks, or terminal cleaning events. Cleanrooms often apply it during quarterly shutdowns, after maintenance, or based on contamination monitoring trends.

What is the difference between iHP, aHP, and VHP decontamination?

iHP (ionized Hydrogen Peroxide) produces ultra-fine, charged droplets that behave like a gas and disperse efficiently. aHP (aerosolized HP) produces larger droplets that may require more contact time. VHP (Vaporized HP) relies on vapor-phase delivery and can offer precise control but sometimes introduces condensation concerns if not tightly managed. ARES can help determine which method fits your facility.

Does whole-room fogging affect room finishes or materials?

Properly formulated hydrogen peroxide systems are compatible with most healthcare and cleanroom surfaces, including stainless steel, epoxy flooring, PVC wall systems, counters, equipment housings, and painted surfaces. We can assess material compatibility for your exact environment.

Can these systems integrate with our existing cleaning SOPs?

Yes. Whole-room decontamination is typically added as a final step after manual cleaning. It can be written directly into SOPs, terminal cleaning workflows, GMP protocols, and audit-ready documentation to support consistency across shifts.

What does a facility assessment include?

An ARES facility assessment reviews room size, HVAC conditions, equipment sensitivity, contamination risks, throughput needs, and regulatory requirements. Based on these factors, we recommend the most appropriate decontamination system and help plan deployment, training, and ongoing support.