Baker Ruskinn InvivO2 Hypoxia Workstation (Models 400, 500, 1000)
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The Baker Ruskinn InvivO2 hypoxia workstation is a combined incubator and sterile workstation that recreates physiological oxygen conditions for the growth and monitoring of mammalian cells, part of the Baker Company laboratory equipment portfolio distributed by ARES Scientific. Also referred to as an InvivO2 physiological cell culture workstation, physoxia workstation, or low-oxygen hypoxia chamber, it allows researchers to study complex cell interactions under true in vivo oxygen levels rather than the hyperoxic conditions of conventional atmospheric culture.
Available as the InvivO2 400, InvivO2 500, and dual-chamber InvivO2 1000, the workstation gives cell biologists and cancer researchers direct hands-in access through cuffed Ezee Sleeve ports and rapid single-plate loading, so cultures move from seeding through assay without leaving the controlled environment. Because it integrates incubation and an aseptic work area in one enclosure, the InvivO2 complements conventional COâ‚‚ incubators for cell culture and pairs naturally with the broader laboratory incubator range for labs building out physiological and stem-cell workflows.
Typical applications include stem-cell cultivation, tissue engineering, cancer and hypoxia-signaling research, and other life-science laboratory programs where oxygen tension shapes results. The InvivO2 supports research and vivarium and research facility teams replicating the low-oxygen environment of tissues such as blood vessels, bone marrow, and lung.
Description
Baker Ruskinn InvivO2 — Product Highlights
- Delivers physiological oxygen (physoxia) control so cells are cultured at the oxygen tension of their native tissue, reducing the hyperoxic stress associated with standard atmospheric culture.
- Combines an incubator and sterile hypoxia workstation in a single enclosure, keeping cultures under continuous controlled conditions from seeding through expansion, assay, and harvest.
- Offers precise Oâ‚‚ and COâ‚‚ regulation with user-defined setpoints, giving reproducible low-oxygen and physoxic environments for demanding cell-interaction studies.
- Provides direct hands-in access via cuffed Ezee Sleeve ports, allowing sample manipulation without gloveboxes and without compromising the internal atmosphere.
- Features an intelligent interlock with heating and oxygen control that automatically matches the main chamber, enabling fast, low-stress transfer of plates and flasks alongside your cell-culture incubator setup.
- Includes internal HEPA filtration for high air-cleanliness ratings within the chamber, supporting contamination-controlled culture conditions.
- Uses a removable Pop-Off front cover for straightforward set-up, instrument placement, and cleaning between projects.
- Supports continuous conditions monitoring and data logging through a touchscreen interface, with remote monitoring and control options for unattended runs.
- Scales across the InvivO2 400, 500, and dual-chamber 1000 models, so throughput can be matched to routine culture or high-capacity research programs, and complements Baker ReCO2ver rapid-recovery incubators in a physiological workflow.
- ARES Scientific is an authorized distributor for the Baker Company, ensuring genuine InvivO2 workstations with full manufacturer warranty and factory support.
Frequently Asked Questions — Baker Ruskinn InvivO2
What is a hypoxia workstation used for?
A hypoxia workstation is used to culture and study cells under low, physiologically relevant oxygen levels instead of standard atmospheric oxygen. The InvivO2 maintains user-defined oxygen, carbon dioxide, temperature, and humidity so researchers can model conditions in tissues such as tumors, bone marrow, and blood vessels for stem-cell, cancer, and tissue-engineering work.
What is the difference between the InvivO2 400, 500, and 1000?
The InvivO2 400 and 500 are single-chamber workstations that differ mainly in interlock size, with the 500 offering a larger interlock than the 400. The InvivO2 1000 is a dual-chamber system with two independently controlled chambers, giving higher capacity or the ability to run two different atmospheres at once.
How is a hypoxia workstation different from a COâ‚‚ incubator?
A conventional COâ‚‚ incubator controls temperature, humidity, and COâ‚‚ but leaves oxygen at atmospheric levels, whereas the InvivO2 adds precise oxygen control and an integrated sterile work area so cells are never exposed to ambient air during handling. Many labs run the InvivO2 alongside standard COâ‚‚ incubators depending on whether oxygen control is required.
Does the InvivO2 require special installation or utilities?
The InvivO2 is a benchtop-style enclosure that requires a suitable power supply and connection to nitrogen and carbon dioxide gas supplies for atmosphere control. It does not require ducting; specific gas, electrical, and space requirements should be confirmed against the manufacturer installation documentation for your model.
What accessories work with the InvivO2 for low-oxygen workflows?
Culture handling can be supported with compatible cell-culture media aspiration systems, and the InvivO2 integrates into wider physiological setups that may include portable physoxia chambers and rapid-recovery incubators for uninterrupted low-oxygen culture.
Technical Specifications — Baker Ruskinn InvivO2 Hypoxia Workstation
| Product type: | Hypoxia / physiological cell culture workstation (incubator and sterile workstation combined) |
| Models: | InvivO2 400, InvivO2 500, InvivO2 1000 (dual chamber) |
| Oxygen (Oâ‚‚) control: | 0.1% to 23.0% |
| Carbon dioxide (COâ‚‚) control: | 0.1% to 30.0% |
| Temperature range: | Ambient +5 °C up to 45 °C |
| Working volume: | 210.3 L per chamber (400 and 500); InvivO2 1000 has two independently controlled 210.3 L chambers |
| Interlock capacity: | 26 L (InvivO2 400); 41 L (InvivO2 500); 49 L (InvivO2 1000) |
| Chambers: | Single chamber (400 / 500); two independently controlled chambers (1000) |
| Filtration: | Internal HEPA filtration |
| Access: | Cuffed Ezee Sleeve ports; intelligent heated interlock; single-plate entry |
| Control & monitoring: | Touchscreen control, direct Oâ‚‚/COâ‚‚ control, continuous monitoring and data logging, remote monitoring/control option |
| Construction / access: | Removable Pop-Off front cover; internal power sockets; narrow and wide culture racks |