Description

Baker ChemoSHIELD® – Product Highlights

• Negative pressure CACI design maintains a contained, leak-tight work environment tested to AGS standard, preventing migration of hazardous drug contaminants and cytotoxic aerosols from the compounding area to the surrounding pharmacy or clinical environment.
• ISO Class 5 (Class 100) air cleanliness is achieved inside the negative pressure chamber through unidirectional HEPA-filtered airflow, supporting USP 800 and USP 797 aseptic compounding requirements for hazardous drug preparation.
• No onboard motor or blower means all static pressure and airflow is supplied by the building exhaust system, eliminating an internal mechanical component that requires routine maintenance and reducing long-term service complexity compared to self-contained hazardous drug isolators.
• ASTM D6978-tested gloves and glove sleeves provide chemotherapy drug-resistant hand protection, with ambidextrous glove positioning in the main chamber giving compounding technicians complete access to the full interior work area during IV admixture and chemotherapy preparation workflows.
• Negative pressure pass-through chamber allows safe and efficient transfer of materials, vials, and compounding supplies into and out of the main chamber without breaking containment or exposing personnel to hazardous drug residue during the transfer process.
• Hinged viewscreen for easy loading allows instruments and equipment to be placed inside the main chamber without disassembly or compromising the negative pressure containment environment, supporting setup flexibility in oncology pharmacy and cGMP isolator applications.
• Pass-through door ambidextrous glove allows manipulation of contents and surface decontamination of materials transferred to or from the main compounding chamber, reducing the risk of hazardous drug surface contamination during material handling and transfer workflows.
• Available in 60-inch and 75-inch width configurations to accommodate different pharmacy footprints, compounding volumes, and equipment layouts in hospital pharmacy cleanrooms, oncology suites, and sterile compounding facilities.
• Sterile interior conditions are maintained alongside hazardous drug containment, supporting preparation of both cytotoxic sterile preparations and non-sterile hazardous compounds under a single platform that addresses personnel protection and product quality simultaneously.
• ARES Scientific is an authorized distributor for Baker, ensuring you receive genuine products with full manufacturer warranty and access to replacement components and technical support for your pharmacy containment isolator.

Frequently Asked Questions – Baker ChemoSHIELD®

What is the Baker ChemoSHIELD® and what does it do?

The Baker ChemoSHIELD® is a compounding aseptic containment isolator (CACI) designed to protect pharmacy personnel from exposure to hazardous drugs, chemotherapy agents, and cytotoxic compounds during IV admixture preparation and sterile compounding workflows; it maintains ISO Class 5 (Class 100) air cleanliness inside a negative pressure, leak-tight enclosure tested to AGS standard, preventing contaminated air from migrating out of the compounding area while preserving aseptic conditions for sterile product preparation.

Is the Baker ChemoSHIELD® compliant with USP 800 and USP 797 requirements?

The ChemoSHIELD® is engineered to support the containment and aseptic processing requirements associated with USP 800 and USP 797 by providing a negative pressure ISO Class 5 environment with leak-tight AGS-tested containment for hazardous drug compounding; facilities should work with their certifying body to confirm that the installed and certified isolator meets all applicable USP chapter requirements for their specific compounding operations, as compliance determinations depend on installation, facility design, and operational procedures in addition to equipment specifications.

How does the ChemoSHIELD® differ from a traditional biological safety cabinet for hazardous drug preparation?

Unlike a traditional biological safety cabinet, the ChemoSHIELD® is a fully enclosed, glove-based isolator with a leak-tight negative pressure chamber tested to AGS standard, which provides a higher level of personnel protection from hazardous drug exposure by eliminating the open sash interface present in Class II BSC designs; additionally, the ChemoSHIELD® has no onboard motor or blower, relying on the building exhaust system for all airflow, which removes a common maintenance requirement found in self-contained BSC units used for hazardous drug handling.

What are the glove specifications for the ChemoSHIELD® and why do they matter?

The ChemoSHIELD® is supplied with ambidextrous gloves and glove sleeves that have been tested to ASTM D6978, the standard specifically evaluating glove resistance to permeation by chemotherapy drugs; ASTM D6978 compliance is a critical specification for hazardous drug compounding isolators because standard laboratory or surgical gloves are not evaluated for chemotherapy drug resistance and may allow drug permeation that standard glove standards do not detect.

Does the ChemoSHIELD® require a dedicated building exhaust connection?

Yes — because the ChemoSHIELD® has no onboard motor or blower, it relies entirely on the facility’s building exhaust system to supply the static pressure and airflow required for negative pressure operation and HEPA-filtered containment; facilities evaluating the ChemoSHIELD® should confirm that their HVAC and exhaust infrastructure can supply the required airflow and static pressure specifications with their Baker representative or facility engineering team prior to installation.

What applications is the Baker ChemoSHIELD® used for?

The ChemoSHIELD® is used for chemotherapy preparation, IV admixture compounding, cytotoxic drug handling, and preparation of other NIOSH-listed hazardous drugs in hospital pharmacy cleanrooms, oncology infusion centers, sterile compounding pharmacies, and pharmaceutical manufacturing environments where simultaneous personnel protection and aseptic product quality are required under a single containment platform.